Alexander Isak and Sven Botman have both been ruled out of Newcastle United’s match against Arsenal this week, as the host’s injury list grows.

NEWCASTLE UPON TYNE, ENGLAND - OCTOBER 25: Newcastle player Alexander Isak reacts after injury forces him to leave the field during the UEFA Champions League match between Newcastle United FC and Borussia Dortmund at St. James Park on October 25, 2023 in Newcastle upon Tyne, England. (Photo by Stu Forster/Getty Images)
NEWCASTLE UPON TYNE, ENGLAND: Newcastle player Alexander Isak reacts after injury forces him to leave the field during the UEFA Champions League match between Newcastle United FC and Borussia Dortmund at St. James Park on October 25, 2023. (Photo by Stu Forster/Getty Images)

Newcastle United face Manchester United away from home in the League Cup in midweek, before hosting Arsenal at St. James’ Park this weekend.

Ahead of the former fixture, Eddie Howe gave some fitness updates on his squad, including ruling a couple of players out of the weekend clash with Arsenal.

Previous reports on Alexander Isak had suggested he could miss the Arsenal match, and Eddie Howe confirmed they’re looking to get the striker back “after the international break”.

Sven Botman has also been ruled out, with Howe saying: “There’s an issue there. We are working through various options to try & diagnose the injury properly. Does he fall into the longer-term category? Yeah, perhaps. But we’re awaiting clarity.”

NEWCASTLE UPON TYNE, ENGLAND - MAY 07: Eddie Howe, Manager of Newcastle United, and Jason Tindall, Assistant Manager of Newcastle United, react during the Premier League match between Newcastle United and Arsenal FC at St. James Park on May 07, 2023 in Newcastle upon Tyne, England. (Photo by Stu Forster/Getty Images)
NEWCASTLE UPON TYNE, ENGLAND: Eddie Howe, Manager of Newcastle United, and Jason Tindall, Assistant Manager of Newcastle United, react during the Premier League match between Newcastle United and Arsenal FC at St. James Park on May 07, 2023. (Photo by Stu Forster/Getty Images)

Newcastle have a number of other existing injury problems, with Harvey Barnes suffering a foot injury, Jacob Murphy looking to need an operation on his shoulder, and Elliot Anderson struggling with a lower back stress fracture.

All three of the above players are unlikely to play before the very end of 2023, so there’s no chance of a return this weekend.

Then there’s young Lewis Miley, who is currently out of action through illness. Howe recently confirmed Miley has glandular fever and would have four weeks of lower physical exertion before building back up.

NEWCASTLE UPON TYNE, ENGLAND - OCTOBER 21: Sandro Tonali of Newcastle looks on from the substitutes bench prior to the Premier League match between Newcastle United and Crystal Palace at St. James Park on October 21, 2023 in Newcastle upon Tyne, England. (Photo by Stu Forster/Getty Images)
NEWCASTLE UPON TYNE, ENGLAND: Sandro Tonali of Newcastle looks on from the substitutes bench prior to the Premier League match between Newcastle United and Crystal Palace at St. James Park on October 21, 2023. (Photo by Stu Forster/Getty Images)

Finally, Sandro Tonali will miss the Arsenal match through suspension, having been banned from football due to his illegal involvement in betting whilst in Italy. His 10-month ban is now underway.

Newcastle will still be able to start all of the players who were involved in their last Premier League fixture, which would mean a lineup like the following: Pope, Trippier, Lascelles, Schar, Burn, Guimaraes, Longstaff, Joelinton, Almiron, Gordon