Hector Bellerin will not take any part as he is now sidelined, reportedly for the next two weeks with a right thigh problem. Arsenal, however, expect to asses him ahead of the game against Liverpool.
Petr Cech has recovered from his hamstring strain and will start in goal.
Sead Kolasinac is still struggling to get fit but he is in line for an appearance on Wednesday night with a late fitness check scheduled.
Mohamed Elneny, who would have been expecting to get his fourth start of the season against the Tangerines, will miss out due to a right thigh issue of his own. He will be out for two weeks.
Laurent Koscielny, who is back in full training, is still targeting a November return to action, as is Dino Mavropanos who is still out with a groin injury.