Olympiacos travel to the Emirates after losing 3-0 at home to Bayern Munich in their opening Champions League game.
Arsenal didn’t do much better, losing away to Dinamo Zagreb in what was a lacklustre and disappointing display.
Both teams need a win if they’re to keep their dreams of progressing to the knock-out stages alive and while Arsenal are favourites to take all three points, it won’t be an easy ride.
Here’s how the teams line up.
Arsenal: Ospina; Bellerin, Koscielny, Gabriel, Gibbs; Cazorla, Coquelin, Ox, Ozil, Alexis; Walcott.
Subs: Cech; Mertesacker, Debuchy; Ramsey, Monreal, Chambers, Campbell.
Olympiacos: Roberto, Elabdellaoui, Botia, Siovas, Salino, Cambiasso, Ksami, Fortounis, Seba, Pardo, Ideye.
Subs: Kapino, Finnbogason, Dominguez, Pulido, Masuaku, Vouros, Hernani.
The @Arsenal team warm up ahead of #AFCvOLY. What are your predictions tonight? pic.twitter.com/2yRcMqYTZ3
— Arsenal FC (@Arsenal) September 29, 2015