Tomas Rosicky has left the Czech camp ahead of the game against Slovakia on Tuesday as he is suffering from a cold.
One of four players to leave before the international break is completed, Rosicky will now return to England to recover and it is not clear if he will be fit to play against Liverpool at the weekend.
The other players who have been excused from their international duty are Chelsea’s Petr Cech, David Limbersky and David Lafata.
The Czech Republic’s next game is a friendly set to take place in Slovakia.
In a press release, the Czech national team manager, Dusan Fitzel, said about letting the players leave “We did so by prior arrangement and took into account the health status of some players.
“The coach, Pavel Vrba, moreover, was notified in advance and will give an opportunity against the Slovak Republic to players who, in the past, have not had adequate representation.”
The Chelsea keeper is suffering from a muscle problem although no further details were given regarding the severity of the injury.
Rosicky picked up his 100th cap for his country in the 1-1 draw with Latvia on Saturday.